3db8: Difference between revisions

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New page: '''Unreleased structure''' The entry 3db8 is ON HOLD until Paper Publication Authors: Elling, R.A., Hanan, E.J., Lew, W., Romanowski, M.J. Description: Crystal structure of an activate...
 
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'''Unreleased structure'''
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[[Image:3db8.jpg|left|200px]]


The entry 3db8 is ON HOLD until Paper Publication
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{{STRUCTURE_3db8|  PDB=3db8  |  SCENE=  }}


Authors: Elling, R.A., Hanan, E.J., Lew, W., Romanowski, M.J.
===Crystal structure of an activated (Thr->Asp) Polo-like kinase 1 (Plk1) catalytic domain in complex with Compound 041===


Description: Crystal structure of an activated (Thr->Asp) Polo-like kinase 1 (Plk1) catalytic domain in complex with Compound 041


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{{ABSTRACT_PUBMED_18790636}}
 
==About this Structure==
3DB8 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Danio_rerio Danio rerio]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DB8 OCA].
 
==Reference==
Design and synthesis of 2-amino-isoxazolopyridines as Polo-like kinase inhibitors., Hanan EJ, Fucini RV, Romanowski MJ, Elling RA, Lew W, Purkey HE, VanderPorten EC, Yang W, Bioorg Med Chem Lett. 2008 Oct 1;18(19):5186-9. Epub 2008 Aug 29. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18790636 18790636]
[[Category: Danio rerio]]
[[Category: Polo kinase]]
[[Category: Single protein]]
[[Category: Elling, R A.]]
[[Category: Hanan, E J.]]
[[Category: Lew, W.]]
[[Category: Romanowski, M J.]]
[[Category: Catalytic domain]]
[[Category: Kinase]]
[[Category: Plk1]]
[[Category: Polo-like kinase 1]]
[[Category: Small-molecule inhibitor]]
[[Category: Transferase]]
 
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Revision as of 10:29, 8 October 2008

File:3db8.jpg

Template:STRUCTURE 3db8

Crystal structure of an activated (Thr->Asp) Polo-like kinase 1 (Plk1) catalytic domain in complex with Compound 041Crystal structure of an activated (Thr->Asp) Polo-like kinase 1 (Plk1) catalytic domain in complex with Compound 041

Template:ABSTRACT PUBMED 18790636

About this StructureAbout this Structure

3DB8 is a Single protein structure of sequence from Danio rerio. Full crystallographic information is available from OCA.

ReferenceReference

Design and synthesis of 2-amino-isoxazolopyridines as Polo-like kinase inhibitors., Hanan EJ, Fucini RV, Romanowski MJ, Elling RA, Lew W, Purkey HE, VanderPorten EC, Yang W, Bioorg Med Chem Lett. 2008 Oct 1;18(19):5186-9. Epub 2008 Aug 29. PMID:18790636

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