3d4n: Difference between revisions

Revision as of 11:50, 23 July 2008

This article has been automatically seeded. Changes to this page should pertain to the PDB entry only and not to the protein or biomolecule in general.

File:3d4n.jpg

Template:STRUCTURE 3d4n

Crystal Structure of Human 11-beta-Hydroxysteroid Dehydrogenase (HSD1) in Complex with Sulfonamide InhibitorCrystal Structure of Human 11-beta-Hydroxysteroid Dehydrogenase (HSD1) in Complex with Sulfonamide Inhibitor

Template:ABSTRACT PUBMED 18553955

About this StructureAbout this Structure

3D4N is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

ReferenceReference

Discovery of Novel, Potent Benzamide Inhibitors of 11beta-Hydroxysteroid Dehydrogenase Type 1 (11beta-HSD1) Exhibiting Oral Activity in an Enzyme Inhibition ex Vivo Model., Julian LD, Wang Z, Bostick T, Caille S, Choi R, Degraffenreid M, Di Y, He X, Hungate RW, Jaen JC, Liu J, Monshouwer M, McMinn D, Rew Y, Sudom A, Sun D, Tu H, Ursu S, Walker N, Yan X, Ye Q, Powers JP, J Med Chem. 2008 Jun 14;. PMID:18553955

Page seeded by OCA on Wed Jul 23 11:50:08 2008

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

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-'''Unreleased structure'''
+{{Seed}}
+[[Image:3d4n.jpg|left|200px]]
-The entry 3d4n is ON HOLD
+<!--
+The line below this paragraph, containing "STRUCTURE_3d4n", creates the "Structure Box" on the page.
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+or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+or leave the SCENE parameter empty for the default display.
+-->
+{{STRUCTURE_3d4n|  PDB=3d4n  |  SCENE=  }}
-Authors: Julian, L.D., Wang, Z., Bostick, T., Caille, S., Choi, R., DeGraffenreid, M., He, X., Hungate, R.W., Jaen, J.C., Liu, J., Monshouwer, M., McMinn, D., Rew, Y., Sudom, A., Sun, D., Tu, H., Ursu, S., Walker, N., Yan, X., Ye, Q., Powers, J.P.
+===Crystal Structure of Human 11-beta-Hydroxysteroid Dehydrogenase (HSD1) in Complex with Sulfonamide Inhibitor===
-Description: Crystal Structure of Human 11-beta-Hydroxysteroid Dehydrogenase (HSD1) in Complex with Sulfonamide Inhibitor
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri Jul 11 13:05:01 2008''
+<!--
+The line below this paragraph, {{ABSTRACT_PUBMED_18553955}}, adds the Publication Abstract to the page
+(as it appears on PubMed at http://www.pubmed.gov), where 18553955 is the PubMed ID number.
+-->
+{{ABSTRACT_PUBMED_18553955}}
+==About this Structure==
+D4N is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3D4N OCA].
+==Reference==
+Discovery of Novel, Potent Benzamide Inhibitors of 11beta-Hydroxysteroid Dehydrogenase Type 1 (11beta-HSD1) Exhibiting Oral Activity in an Enzyme Inhibition ex Vivo Model., Julian LD, Wang Z, Bostick T, Caille S, Choi R, Degraffenreid M, Di Y, He X, Hungate RW, Jaen JC, Liu J, Monshouwer M, McMinn D, Rew Y, Sudom A, Sun D, Tu H, Ursu S, Walker N, Yan X, Ye Q, Powers JP, J Med Chem. 2008 Jun 14;. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18553955 18553955]
+[[Category: 11-beta-hydroxysteroid dehydrogenase]]
+[[Category: Homo sapiens]]
+[[Category: Single protein]]
+[[Category: Liu, J.]]
+[[Category: Sudom, A.]]
+[[Category: Walker, N P.]]
+[[Category: Wang, Z.]]
+[[Category: 11beta]]
+[[Category: Dehydrogenase]]
+[[Category: Endoplasmic reticulum]]
+[[Category: Glycoprotein]]
+[[Category: Hydroxysteroid]]
+[[Category: Lipid metabolism]]
+[[Category: Membrane]]
+[[Category: Microsome]]
+[[Category: Nadp]]
+[[Category: Oxidoreductase]]
+[[Category: Polymorphism]]
+[[Category: Signal-anchor]]
+[[Category: Steroid metabolism]]
+[[Category: Transmembrane]]
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 23 11:50:08 2008''