3cwj: Difference between revisions

Revision as of 11:30, 22 April 2009

This article has been automatically seeded. Changes to this page should pertain to the PDB entry only and not to the protein or biomolecule in general.

File:3cwj.jpg

Template:STRUCTURE 3cwj

Crystal structure of hcv ns5b polymerase with a novel pyridazinone inhibitorCrystal structure of hcv ns5b polymerase with a novel pyridazinone inhibitor

Template:ABSTRACT PUBMED 18662878

About this StructureAbout this Structure

3CWJ is a 2 chains structure of sequences from Hepatitis c virus. Full crystallographic information is available from OCA.

ReferenceReference

^{[xtra 1]}

↑ Ellis DA, Blazel JK, Webber SE, Tran CV, Dragovich PS, Sun Z, Ruebsam F, McGuire HM, Xiang AX, Zhao J, Li LS, Zhou Y, Han Q, Kissinger CR, Showalter RE, Lardy M, Shah AM, Tsan M, Patel R, LeBrun LA, Kamran R, Bartkowski DM, Nolan TG, Norris DA, Sergeeva MV, Kirkovsky L. 4-(1,1-Dioxo-1,4-dihydro-1lambda6-benzo[1,4]thiazin-3-yl)-5-hydroxy-2H-pyr idazin-3-ones as potent inhibitors of HCV NS5B polymerase. Bioorg Med Chem Lett. 2008 Aug 15;18(16):4628-32. Epub 2008 Jul 10. PMID:18662878 doi:10.1016/j.bmcl.2008.07.014

Page seeded by OCA on Wed Apr 22 11:30:21 2009

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

[1] Ellis DA, Blazel JK, Webber SE, Tran CV, Dragovich PS, Sun Z, Ruebsam F, McGuire HM, Xiang AX, Zhao J, Li LS, Zhou Y, Han Q, Kissinger CR, Showalter RE, Lardy M, Shah AM, Tsan M, Patel R, LeBrun LA, Kamran R, Bartkowski DM, Nolan TG, Norris DA, Sergeeva MV, Kirkovsky L. 4-(1,1-Dioxo-1,4-dihydro-1lambda6-benzo[1,4]thiazin-3-yl)-5-hydroxy-2H-pyr idazin-3-ones as potent inhibitors of HCV NS5B polymerase. Bioorg Med Chem Lett. 2008 Aug 15;18(16):4628-32. Epub 2008 Jul 10. PMID:18662878 doi:10.1016/j.bmcl.2008.07.014

[xtra 1]

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-'''Unreleased structure'''
+{{Seed}}
+[[Image:3cwj.jpg|left|200px]]
-The entry 3cwj is ON HOLD  until Apr 21 2010
+<!--
+The line below this paragraph, containing "STRUCTURE_3cwj", creates the "Structure Box" on the page.
+You may change the PDB parameter (which sets the PDB file loaded into the applet)
+or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+or leave the SCENE parameter empty for the default display.
+-->
+{{STRUCTURE_3cwj|  PDB=3cwj  |  SCENE=  }}
-Authors: Han, Q., Showalter, R.E., Zhao, Q., Kissinger, C.R.
+===Crystal structure of hcv ns5b polymerase with a novel pyridazinone inhibitor===
-Description: Crystal structure of hcv ns5b polymerase with a novel pyridazinone inhibitor
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri Jul 11 13:04:23 2008''
+<!--
+The line below this paragraph, {{ABSTRACT_PUBMED_18662878}}, adds the Publication Abstract to the page
+(as it appears on PubMed at http://www.pubmed.gov), where 18662878 is the PubMed ID number.
+-->
+{{ABSTRACT_PUBMED_18662878}}
+==About this Structure==
+CWJ is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Hepatitis_c_virus Hepatitis c virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CWJ OCA].
+==Reference==
+<ref group="xtra">PMID:18662878</ref><references group="xtra"/>
+[[Category: Hepatitis c virus]]
+[[Category: RNA-directed RNA polymerase]]
+[[Category: Han, Q.]]
+[[Category: Kissinger, C R.]]
+[[Category: Showalter, R E.]]
+[[Category: Zhao, Q.]]
+[[Category: Hepatitis]]
+[[Category: Protein-ligand complex]]
+[[Category: Rna replication]]
+[[Category: Rna-binding]]
+[[Category: Rna-directed rna polymerase]]
+[[Category: Transferase]]
+[[Category: Viral protein]]
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Apr 22 11:30:21 2009''