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New page: left|200px<br /><applet load="1bo6" size="450" color="white" frame="true" align="right" spinBox="true" caption="1bo6, resolution 2.10Å" /> '''ESTROGEN SULFOTRANSF... |
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[[Image:1bo6.gif|left|200px]]<br /><applet load="1bo6" size=" | [[Image:1bo6.gif|left|200px]]<br /><applet load="1bo6" size="350" color="white" frame="true" align="right" spinBox="true" | ||
caption="1bo6, resolution 2.10Å" /> | caption="1bo6, resolution 2.10Å" /> | ||
'''ESTROGEN SULFOTRANSFERASE WITH INACTIVE COFACTOR PAP AND VANADATE'''<br /> | '''ESTROGEN SULFOTRANSFERASE WITH INACTIVE COFACTOR PAP AND VANADATE'''<br /> | ||
==Overview== | ==Overview== | ||
The structure of estrogen sulphotransferase has been solved in the | The structure of estrogen sulphotransferase has been solved in the presence of inactive cofactor PAP and substrate 17 beta-estradiol. This structure reveals structural similarities between cytosolic sulphotransferases and nucleotide kinases. | ||
==About this Structure== | ==About this Structure== | ||
1BO6 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus] with VO4 and A3P as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Estrone_sulfotransferase Estrone sulfotransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.8.2.4 2.8.2.4] Full crystallographic information is available from [http:// | 1BO6 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus] with <scene name='pdbligand=VO4:'>VO4</scene> and <scene name='pdbligand=A3P:'>A3P</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Estrone_sulfotransferase Estrone sulfotransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.8.2.4 2.8.2.4] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BO6 OCA]. | ||
==Reference== | ==Reference== | ||
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[[Category: Kakuta, Y.]] | [[Category: Kakuta, Y.]] | ||
[[Category: Negishi, M.]] | [[Category: Negishi, M.]] | ||
[[Category: Pedersen, L | [[Category: Pedersen, L C.]] | ||
[[Category: A3P]] | [[Category: A3P]] | ||
[[Category: VO4]] | [[Category: VO4]] | ||
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[[Category: vanadate]] | [[Category: vanadate]] | ||
''Page seeded by [http:// | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 11:57:17 2008'' | ||
Revision as of 12:57, 21 February 2008
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ESTROGEN SULFOTRANSFERASE WITH INACTIVE COFACTOR PAP AND VANADATE
OverviewOverview
The structure of estrogen sulphotransferase has been solved in the presence of inactive cofactor PAP and substrate 17 beta-estradiol. This structure reveals structural similarities between cytosolic sulphotransferases and nucleotide kinases.
About this StructureAbout this Structure
1BO6 is a Single protein structure of sequence from Mus musculus with and as ligands. Active as Estrone sulfotransferase, with EC number 2.8.2.4 Full crystallographic information is available from OCA.
ReferenceReference
Crystal structure of estrogen sulphotransferase., Kakuta Y, Pedersen LG, Carter CW, Negishi M, Pedersen LC, Nat Struct Biol. 1997 Nov;4(11):904-8. PMID:9360604
Page seeded by OCA on Thu Feb 21 11:57:17 2008