1bl0: Difference between revisions
New page: left|200px<br /><applet load="1bl0" size="450" color="white" frame="true" align="right" spinBox="true" caption="1bl0, resolution 2.300Å" /> '''MULTIPLE ANTIBIOTIC... |
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[[Image:1bl0.gif|left|200px]]<br /><applet load="1bl0" size=" | [[Image:1bl0.gif|left|200px]]<br /><applet load="1bl0" size="350" color="white" frame="true" align="right" spinBox="true" | ||
caption="1bl0, resolution 2.300Å" /> | caption="1bl0, resolution 2.300Å" /> | ||
'''MULTIPLE ANTIBIOTIC RESISTANCE PROTEIN (MARA)/DNA COMPLEX'''<br /> | '''MULTIPLE ANTIBIOTIC RESISTANCE PROTEIN (MARA)/DNA COMPLEX'''<br /> | ||
==Overview== | ==Overview== | ||
A crystal structure for a member of the AraC prokaryotic transcriptional | A crystal structure for a member of the AraC prokaryotic transcriptional activator family, MarA, in complex with its cognate DNA-binding site is described. MarA consists of two similar subdomains, each containing a helix-turn-helix DNA-binding motif. The two recognition helices of the motifs are inserted into adjacent major groove segments on the same face of the DNA but are separated by only 27 A thereby bending the DNA by approximately 35 degrees. Extensive interactions between the recognition helices and the DNA major groove provide the sequence specificity. | ||
==About this Structure== | ==About this Structure== | ||
1BL0 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http:// | 1BL0 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BL0 OCA]. | ||
==Reference== | ==Reference== | ||
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[[Category: Single protein]] | [[Category: Single protein]] | ||
[[Category: Davies, S.]] | [[Category: Davies, S.]] | ||
[[Category: Martin, J | [[Category: Martin, J L.]] | ||
[[Category: Rhee, R | [[Category: Rhee, R G.]] | ||
[[Category: Rosner, D | [[Category: Rosner, D R.]] | ||
[[Category: transcriptional activator; a bipartite helix-turn-helix protein]] | [[Category: transcriptional activator; a bipartite helix-turn-helix protein]] | ||
''Page seeded by [http:// | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 11:56:25 2008'' | ||
