Nucleosomes: Difference between revisions
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An intact nucleosome may be viewed in the PDB entry [[1aoi]]. The picture here shows the eight histone proteins as tubes that follow the protein chain, and shows the DNA as thinner tubes that follow the two strands as they circle around the protein octamer. The tails of the eight protein chains, seen extending outward from the center, are actually longer in reality. But, since they are so long and flexible, they are disordered in the crystal and cannot be seen. The one long chain at lower left gives a good indication of what the others might look like, if we were able to see the nucleosome inside a cell. Keep in mind that this structure only includes a short piece of DNA. In reality, these little nucleosomes are arrayed by the millions along long strands of DNA. | An intact nucleosome may be viewed in the PDB entry [[1aoi]]. The picture here shows the eight histone proteins as tubes that follow the protein chain, and shows the DNA as thinner tubes that follow the two strands as they circle around the protein octamer. The tails of the eight protein chains, seen extending outward from the center, are actually longer in reality. But, since they are so long and flexible, they are disordered in the crystal and cannot be seen. The one long chain at lower left gives a good indication of what the others might look like, if we were able to see the nucleosome inside a cell. Keep in mind that this structure only includes a short piece of DNA. In reality, these little nucleosomes are arrayed by the millions along long strands of DNA. | ||
== | == '''Content Donators''' == | ||
* Content adapted with permission from David S. Goodsell's [http://mgl.scripps.edu/people/goodsell/pdb/pdb7/pdb7_1.html Molecule of the Month on Nucleosomes]. | Currently (June 22 2008), some of the textual and image content of this page is the work of [[David S. Goodsell]], who has given permission for its inclusion in [[Proteopedia]]: | ||
* '''Content adapted with permission from David S. Goodsell's [http://mgl.scripps.edu/people/goodsell/pdb/pdb7/pdb7_1.html Molecule of the Month on Nucleosomes].''' | |||