2zb0: Difference between revisions

Revision as of 19:12, 27 July 2008

This article has been automatically seeded. Changes to this page should pertain to the PDB entry only and not to the protein or biomolecule in general.

File:2zb0.png

Template:STRUCTURE 2zb0

Crystal structure of P38 in complex with biphenyl amide inhibitorCrystal structure of P38 in complex with biphenyl amide inhibitor

Template:ABSTRACT PUBMED 18006306

About this StructureAbout this Structure

2ZB0 is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

ReferenceReference

Biphenyl amide p38 kinase inhibitors 1: Discovery and binding mode., Angell RM, Bamborough P, Cleasby A, Cockerill SG, Jones KL, Mooney CJ, Somers DO, Walker AL, Bioorg Med Chem Lett. 2008 Jan 1;18(1):318-23. Epub 2007 Nov 19. PMID:18006306

Biphenyl amide p38 kinase inhibitors 2: Optimisation and SAR., Angell RM, Angell TD, Bamborough P, Brown D, Brown M, Buckton JB, Cockerill SG, Edwards CD, Jones KL, Longstaff T, Smee PA, Smith KJ, Somers DO, Walker AL, Willson M, Bioorg Med Chem Lett. 2008 Jan 1;18(1):324-8. Epub 2007 Oct 17. PMID:17981461

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Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

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 {{STRUCTURE_2zb0|  PDB=2zb0  |  SCENE=  }}
-'''Crystal structure of P38 in complex with biphenyl amide inhibitor'''
+===Crystal structure of P38 in complex with biphenyl amide inhibitor===
-==Overview==
+<!--
-The biphenyl amides (BPAs) are a novel series of p38 MAP kinase inhibitors. The discovery of the series through structure-based focused screening is described, and the binding mode of the compounds is explained with reference to X-ray crystal structures.
+The line below this paragraph, {{ABSTRACT_PUBMED_18006306}}, adds the Publication Abstract to the page
+(as it appears on PubMed at http://www.pubmed.gov), where 18006306 is the PubMed ID number.
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+{{ABSTRACT_PUBMED_18006306}}
 ==About this Structure==
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 ==Reference==
 Biphenyl amide p38 kinase inhibitors 1: Discovery and binding mode., Angell RM, Bamborough P, Cleasby A, Cockerill SG, Jones KL, Mooney CJ, Somers DO, Walker AL, Bioorg Med Chem Lett. 2008 Jan 1;18(1):318-23. Epub 2007 Nov 19. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18006306 18006306]
+Biphenyl amide p38 kinase inhibitors 2: Optimisation and SAR., Angell RM, Angell TD, Bamborough P, Brown D, Brown M, Buckton JB, Cockerill SG, Edwards CD, Jones KL, Longstaff T, Smee PA, Smith KJ, Somers DO, Walker AL, Willson M, Bioorg Med Chem Lett. 2008 Jan 1;18(1):324-8. Epub 2007 Oct 17. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17981461 17981461]
 [[Category: Homo sapiens]]
 [[Category: Mitogen-activated protein kinase]]
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 [[Category: Serine/threonine protein kinase]]
 [[Category: Transferase]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May  4 20:06:14 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 19:12:02 2008''