2ojj: Difference between revisions

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

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-[[Image:2ojj.gif|left|200px]]
+{{Seed}}
+[[Image:2ojj.png|left|200px]]
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 {{STRUCTURE_2ojj|  PDB=2ojj  |  SCENE=  }}
-'''Crystal structure of ERK2 in complex with (S)-N-(1-(3-chloro-4-fluorophenyl)-2-hydroxyethyl)-4-(4-(3-chlorophenyl)-1H-pyrazol-3-yl)-1H-pyrrole-2-carboxamide'''
+===Crystal structure of ERK2 in complex with (S)-N-(1-(3-chloro-4-fluorophenyl)-2-hydroxyethyl)-4-(4-(3-chlorophenyl)-1H-pyrazol-3-yl)-1H-pyrrole-2-carboxamide===
-==Overview==
+<!--
-The Ras/Raf/MEK/ERK signal transduction is a key oncogenic pathway implicated in a variety of human cancers. We have identified a novel series of pyrazolylpyrroles as inhibitors of ERK. Aided by the discovery of two distinct binding modes for the pyrazolylpyrrole scaffold, structure-guided optimization culminated in the discovery of 6p, a potent and selective inhibitor of ERK.
+The line below this paragraph, {{ABSTRACT_PUBMED_17300186}}, adds the Publication Abstract to the page
+(as it appears on PubMed at http://www.pubmed.gov), where 17300186 is the PubMed ID number.
+-->
+{{ABSTRACT_PUBMED_17300186}}
 ==About this Structure==
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 [[Category: Xie, X.]]
 [[Category: Kinase inhibitor]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May  4 11:02:41 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 13:37:06 2008''