2oi0: Difference between revisions

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

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-[[Image:2oi0.jpg|left|200px]]
+{{Seed}}
+[[Image:2oi0.png|left|200px]]
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 {{STRUCTURE_2oi0|  PDB=2oi0  |  SCENE=  }}
-'''Crystal structure analysis 0f the TNF-a Coverting Enzyme (TACE) in complexed with Aryl-sulfonamide'''
+===Crystal structure analysis 0f the TNF-a Coverting Enzyme (TACE) in complexed with Aryl-sulfonamide===
-==Overview==
+<!--
-A series of potent thiol-containing aryl sulfonamide TACE inhibitors was designed and synthesized. The SAR and MMP selectivity of the series were investigated. In particular, compound 4b has shown excellent in vitro potency against the isolated TACE enzyme and good selectivity over MMP-2, -7, -8, -9, and -13. The X-ray structure of 4b bound to TACE was obtained.
+The line below this paragraph, {{ABSTRACT_PUBMED_17289381}}, adds the Publication Abstract to the page
+(as it appears on PubMed at http://www.pubmed.gov), where 17289381 is the PubMed ID number.
+-->
+{{ABSTRACT_PUBMED_17289381}}
 ==About this Structure==
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 [[Category: Tace inhibitor]]
 [[Category: Tnf-a coverting enzyme]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May  4 10:57:56 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 23:17:21 2008''