2o5k: Difference between revisions

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

@@ Line 1: / Line 1: @@
-[[Image:2o5k.jpg|left|200px]]
+{{Seed}}
+[[Image:2o5k.png|left|200px]]
 <!--
@@ Line 9: / Line 10: @@
 {{STRUCTURE_2o5k|  PDB=2o5k  |  SCENE=  }}
-'''Crystal Structure of GSK3beta in complex with a benzoimidazol inhibitor'''
+===Crystal Structure of GSK3beta in complex with a benzoimidazol inhibitor===
-==Overview==
+<!--
-A hydroxy functional group was introduced as the hydrogen bond donor and acceptor at the hinge region of protein kinase in order to develop novel ATP-competitive inhibitors. Several derivatives of 7-hydroxyl-1H-benzoimidazole were designed as inhibitors of glycogen synthase kinase-3beta with the help of ab initio calculations and a docking study. Enzymatic assay and an X-ray complex study showed that these designed compounds were highly potent ATP-competitive inhibitors.
+The line below this paragraph, {{ABSTRACT_PUBMED_17764934}}, adds the Publication Abstract to the page
+(as it appears on PubMed at http://www.pubmed.gov), where 17764934 is the PubMed ID number.
+-->
+{{ABSTRACT_PUBMED_17764934}}
 ==About this Structure==
@@ Line 34: / Line 38: @@
 [[Category: Gsk3beta]]
 [[Category: Transferase]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May  4 10:21:17 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 17:11:39 2008''