2nmv: Difference between revisions

Revision as of 09:31, 28 July 2008

This article has been automatically seeded. Changes to this page should pertain to the PDB entry only and not to the protein or biomolecule in general.

File:2nmv.png

Template:STRUCTURE 2nmv

Damage detection by the UvrABC pathway: Crystal structure of UvrB bound to fluorescein-adducted DNADamage detection by the UvrABC pathway: Crystal structure of UvrB bound to fluorescein-adducted DNA

Template:ABSTRACT PUBMED 17097086

About this StructureAbout this Structure

2NMV is a Protein complex structure of sequences from Bacillus subtilis. Full crystallographic information is available from OCA.

ReferenceReference

Damage detection by the UvrABC pathway: crystal structure of UvrB bound to fluorescein-adducted DNA., Waters TR, Eryilmaz J, Geddes S, Barrett TE, FEBS Lett. 2006 Nov 27;580(27):6423-7. Epub 2006 Nov 3. PMID:17097086

Page seeded by OCA on Mon Jul 28 09:31:06 2008

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

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-'''Damage detection by the UvrABC pathway: Crystal structure of UvrB bound to fluorescein-adducted DNA'''
+===Damage detection by the UvrABC pathway: Crystal structure of UvrB bound to fluorescein-adducted DNA===
-==Overview==
+<!--
-UvrB is the damage recognition element of the highly conserved UvrABC pathway that functions in the removal of bulky DNA adducts. Pivotal to this is the formation of a damage detection complex that relies on the ability of UvrB to locate and sequester diverse lesions. Whilst structures of UvrB bound to DNA have recently been reported, none address the issue of lesion recognition. Here, we describe the crystal structure of UvrB bound to a pentanucleotide containing a single fluorescein-adducted thymine that reveals a unique mechanism for damage detection entirely dependent on the exclusion of lesions larger than an undamaged nucleotide.
+The line below this paragraph, {{ABSTRACT_PUBMED_17097086}}, adds the Publication Abstract to the page
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+{{ABSTRACT_PUBMED_17097086}}
 ==About this Structure==
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 [[Category: Protein-dna complex]]
 [[Category: T-fluorescein]]
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