2i6z: Difference between revisions

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{{STRUCTURE_2i6z|  PDB=2i6z  |  SCENE=  }}  
{{STRUCTURE_2i6z|  PDB=2i6z  |  SCENE=  }}  


'''X-ray diffraction studies of adducts between anticancer platinum drugs and hen egg white lysozyme'''
===X-ray diffraction studies of adducts between anticancer platinum drugs and hen egg white lysozyme===




==Overview==
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The interactions of cisplatin and its analogues, transplatin, carboplatin and oxaliplatin, with hen egg white lysozyme were analysed through ESI mass spectrometry, and the resulting metallodrug-protein adducts identified; the X-ray crystal structure of the cisplatin lysozyme derivative, solved at 1.9 A resolution, reveals selective platination of imidazole Nepsilon of His15.
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==About this Structure==
==About this Structure==
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[[Category: Cisplatin-lysozyme adduct]]
[[Category: Cisplatin-lysozyme adduct]]
[[Category: Hydrolase]]
[[Category: Hydrolase]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May  4 07:09:28 2008''
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 13:26:56 2008''

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