2i0h: Difference between revisions

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

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-[[Image:2i0h.gif|left|200px]]
+{{Seed}}
+[[Image:2i0h.png|left|200px]]
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 {{STRUCTURE_2i0h|  PDB=2i0h  |  SCENE=  }}
-'''The structure of p38alpha in complex with an arylpyridazinone'''
+===The structure of p38alpha in complex with an arylpyridazinone===
-==Overview==
+<!--
-p38 inhibitors based on 3,4-dihydropyrido[4,3-d]pyrimidazin-2-one template were synthesized and their SAR explored. Benchmark compounds 30, 35, and 36 were found to be potent against the enzyme. Crystal structure of p38 in complex with 30 indicated a key pi-stacking interaction with the pendant tyrosine residue-35 in the glycine-rich loop.
+The line below this paragraph, {{ABSTRACT_PUBMED_16945533}}, adds the Publication Abstract to the page
+(as it appears on PubMed at http://www.pubmed.gov), where 16945533 is the PubMed ID number.
+-->
+{{ABSTRACT_PUBMED_16945533}}
 ==About this Structure==
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 [[Category: Inhibitor design]]
 [[Category: Serine/threonine kinase]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May  4 06:55:54 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 11:44:49 2008''