2hwq: Difference between revisions

From Proteopedia
Jump to navigation Jump to search
No edit summary
No edit summary
Line 1: Line 1:
[[Image:2hwq.jpg|left|200px]]
{{Seed}}
[[Image:2hwq.png|left|200px]]


<!--
<!--
Line 9: Line 10:
{{STRUCTURE_2hwq|  PDB=2hwq  |  SCENE=  }}  
{{STRUCTURE_2hwq|  PDB=2hwq  |  SCENE=  }}  


'''Structural basis for the structure-activity relationships of Peroxisome Proliferator-Activated Receptor agonists'''
===Structural basis for the structure-activity relationships of Peroxisome Proliferator-Activated Receptor agonists===




==Overview==
<!--
Type 2 diabetes has rapidly reached an epidemic proportion becoming a major threat to global public health. PPAR agonists have emerged as a leading class of oral antidiabetic drugs. We report a structure biology analysis of novel indole-based PPAR agonists to explain the structure-activity relationships and present a critical analysis of reasons for change in selectivity with change in the orientation of the same scaffolds. The results would be helpful in designing novel PPAR agonists.
The line below this paragraph, {{ABSTRACT_PUBMED_17034149}}, adds the Publication Abstract to the page
(as it appears on PubMed at http://www.pubmed.gov), where 17034149 is the PubMed ID number.
-->
{{ABSTRACT_PUBMED_17034149}}


==About this Structure==
==About this Structure==
Line 30: Line 34:
[[Category: Ligand binding protein]]
[[Category: Ligand binding protein]]
[[Category: Ppar]]
[[Category: Ppar]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May  4 06:48:26 2008''
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 00:45:33 2008''

Revision as of 00:45, 28 July 2008

File:2hwq.png

Template:STRUCTURE 2hwq

Structural basis for the structure-activity relationships of Peroxisome Proliferator-Activated Receptor agonistsStructural basis for the structure-activity relationships of Peroxisome Proliferator-Activated Receptor agonists

Template:ABSTRACT PUBMED 17034149

About this StructureAbout this Structure

2HWQ is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

ReferenceReference

Structural basis for the structure-activity relationships of peroxisome proliferator-activated receptor agonists., Mahindroo N, Peng YH, Lin CH, Tan UK, Prakash E, Lien TW, Lu IL, Lee HJ, Hsu JT, Chen X, Liao CC, Lyu PC, Chao YS, Wu SY, Hsieh HP, J Med Chem. 2006 Oct 19;49(21):6421-4. PMID:17034149

Page seeded by OCA on Mon Jul 28 00:45:33 2008

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA