2ieh: Difference between revisions
New page: left|200px<br /> <applet load="2ieh" size="450" color="white" frame="true" align="right" spinBox="true" caption="2ieh, resolution 2.7Å" /> '''Crystal structure of... |
No edit summary |
||
Line 1: | Line 1: | ||
[[Image:2ieh.gif|left|200px]]<br /> | [[Image:2ieh.gif|left|200px]]<br /><applet load="2ieh" size="350" color="white" frame="true" align="right" spinBox="true" | ||
<applet load="2ieh" size=" | |||
caption="2ieh, resolution 2.7Å" /> | caption="2ieh, resolution 2.7Å" /> | ||
'''Crystal structure of human kinesin Eg5 in complex with (R)-mon97, a new monastrol-based inhibitor that binds as (R)-enantiomer'''<br /> | '''Crystal structure of human kinesin Eg5 in complex with (R)-mon97, a new monastrol-based inhibitor that binds as (R)-enantiomer'''<br /> | ||
==About this Structure== | ==About this Structure== | ||
2IEH is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with MG, K, CL, ADP, MOY and PG4 as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Plus-end-directed_kinesin_ATPase Plus-end-directed kinesin ATPase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.4.4 3.6.4.4] Full crystallographic information is available from [http:// | 2IEH is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=MG:'>MG</scene>, <scene name='pdbligand=K:'>K</scene>, <scene name='pdbligand=CL:'>CL</scene>, <scene name='pdbligand=ADP:'>ADP</scene>, <scene name='pdbligand=MOY:'>MOY</scene> and <scene name='pdbligand=PG4:'>PG4</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Plus-end-directed_kinesin_ATPase Plus-end-directed kinesin ATPase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.4.4 3.6.4.4] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IEH OCA]. | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Plus-end-directed kinesin ATPase]] | [[Category: Plus-end-directed kinesin ATPase]] | ||
Line 20: | Line 19: | ||
[[Category: flanked by three alpha-helices on each side]] | [[Category: flanked by three alpha-helices on each side]] | ||
''Page seeded by [http:// | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 17:51:49 2008'' |