2ara: Difference between revisions

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-[[Image:2ara.gif|left|200px]]
+{{Seed}}
+[[Image:2ara.png|left|200px]]
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 {{STRUCTURE_2ara|  PDB=2ara  |  SCENE=  }}
-'''APO FORM OF ESCHERICHIA COLI REGULATORY PROTEIN ARAC'''
+===APO FORM OF ESCHERICHIA COLI REGULATORY PROTEIN ARAC===
-==Overview==
+<!--
-The crystal structure of the arabinose-binding and dimerization domain of the Escherchia coli gene regulatory protein AraC was determined in the presence and absence of L-arabinose. The 1.5 angstrom structure of the arabinose-bound molecule shows that the protein adopts an unusual fold, binding sugar within a beta barrel and completely burying the arabinose with the amino-terminal arm of the protein. Dimer contacts in the presence of arabinose are mediated by an antiparallel coiled-coil. In the 2.8 angstrom structure of the uncomplexed protein, the amino-terminal arm is disordered, uncovering the sugar-binding pocket and allowing it to serve as an oligomerization interface. The ligand-gated oligomerization as seen in AraC provides the basis of a plausible mechanism for modulating the protein's DNA-looping properties.
+The line below this paragraph, {{ABSTRACT_PUBMED_9103202}}, adds the Publication Abstract to the page
+(as it appears on PubMed at http://www.pubmed.gov), where 9103202 is the PubMed ID number.
+-->
+{{ABSTRACT_PUBMED_9103202}}
 ==About this Structure==
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 [[Category: Jelly-roll]]
 [[Category: Transcription regulation]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May  3 19:22:39 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 04:21:16 2008''