2a4n: Difference between revisions

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-[[Image:2a4n.gif|left|200px]]
+{{Seed}}
+[[Image:2a4n.png|left|200px]]
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 {{STRUCTURE_2a4n|  PDB=2a4n  |  SCENE=  }}
-'''Crystal structure of aminoglycoside 6'-N-acetyltransferase complexed with coenzyme A'''
+===Crystal structure of aminoglycoside 6'-N-acetyltransferase complexed with coenzyme A===
-==Overview==
+<!--
-The aminoglycoside-modifying enzyme aminoglycoside 6'-N-acetyltransferase type Ii [AAC(6')-Ii] has been crystallized with its cofactor coenzyme A in space group C222(1), with unit-cell parameters a = 71.5, b = 127.4, c = 76.9 A and one physiologically relevant dimer species per asymmetric unit. The space group previously observed for this complex was P2(1)2(1)2(1), with two dimers per asymmetric unit. By comparing the six available protomer structures of the AAC(6')-Ii-CoA complex, it has been possible to identify regions of plasticity within the protein. Normal-mode analysis of this complex suggests that this plasticity is not an artefact of crystal-packing forces, but that the region of the protomer that displays multiple conformations is intrinsically flexible. It is conjectured that the flexibility is relevant for the cooperative activity observed for the enzyme.
+The line below this paragraph, {{ABSTRACT_PUBMED_16131761}}, adds the Publication Abstract to the page
+(as it appears on PubMed at http://www.pubmed.gov), where 16131761 is the PubMed ID number.
+-->
+{{ABSTRACT_PUBMED_16131761}}
 ==About this Structure==
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 [[Category: Alpha beta protein]]
 [[Category: N-acetyl transferase]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May  3 18:35:53 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 11:14:06 2008''