1zaf: Difference between revisions

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{{Seed}}
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{{STRUCTURE_1zaf|  PDB=1zaf  |  SCENE=  }}  
{{STRUCTURE_1zaf|  PDB=1zaf  |  SCENE=  }}  


'''Crystal structure of estrogen receptor beta complexed with 3-Bromo-6-hydroxy-2-(4-hydroxy-phenyl)-inden-1-one'''
===Crystal structure of estrogen receptor beta complexed with 3-Bromo-6-hydroxy-2-(4-hydroxy-phenyl)-inden-1-one===




==Overview==
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The syntheses of a series of 2-arylindene-1-ones as potent ligands of ERbeta and ERalpha are described. Several compounds exhibited high potency and moderate selectivity for the ERbeta receptor. X-ray and modeling studies were used to understand ligand binding orientation and observed affinity.
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{{ABSTRACT_PUBMED_15876535}}


==About this Structure==
==About this Structure==
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[[Category: Nuclear receptor]]
[[Category: Nuclear receptor]]
[[Category: Transcription factor]]
[[Category: Transcription factor]]
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