1xsn: Difference between revisions

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{{STRUCTURE_1xsn|  PDB=1xsn  |  SCENE=  }}  
{{STRUCTURE_1xsn|  PDB=1xsn  |  SCENE=  }}  


'''Crystal Structure of human DNA polymerase lambda in complex with a one nucleotide DNA gap and ddTTP'''
===Crystal Structure of human DNA polymerase lambda in complex with a one nucleotide DNA gap and ddTTP===




==Overview==
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Pol lambda is a family X member believed to fill short gaps during DNA repair. Here we report crystal structures of Pol lambda representing three steps in filling a single-nucleotide gap. These structures indicate that, unlike other DNA polymerases, Pol lambda does not undergo large subdomain movements during catalysis, and they provide a clear characterization of the geometry and stereochemistry of the in-line nucleotidyl transfer reaction.
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==About this Structure==
==About this Structure==
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[[Category: Helix-hairpin-helix]]
[[Category: Helix-hairpin-helix]]
[[Category: Protein-dna complex]]
[[Category: Protein-dna complex]]
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