1w7x: Difference between revisions

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[[Image:1w7x.jpg|left|200px]]
{{Seed}}
[[Image:1w7x.png|left|200px]]


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{{STRUCTURE_1w7x|  PDB=1w7x  |  SCENE=  }}  
{{STRUCTURE_1w7x|  PDB=1w7x  |  SCENE=  }}  


'''FACTOR7- 413 COMPLEX'''
===FACTOR7- 413 COMPLEX===




==Overview==
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We describe the structure-based design and synthesis of highly potent, orally bioavailable tissue factor/factor VIIa inhibitors which interfere with the coagulation cascade by selective inhibition of the extrinsic pathway.
The line below this paragraph, {{ABSTRACT_PUBMED_16213138}}, adds the Publication Abstract to the page
(as it appears on PubMed at http://www.pubmed.gov), where 16213138 is the PubMed ID number.
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{{ABSTRACT_PUBMED_16213138}}


==About this Structure==
==About this Structure==
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[[Category: Enzyme complex]]
[[Category: Enzyme complex]]
[[Category: Serine protease]]
[[Category: Serine protease]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May  3 13:16:54 2008''
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 05:08:10 2008''

Revision as of 05:08, 28 July 2008

File:1w7x.png

Template:STRUCTURE 1w7x

FACTOR7- 413 COMPLEXFACTOR7- 413 COMPLEX

Template:ABSTRACT PUBMED 16213138

About this StructureAbout this Structure

1W7X is a Protein complex structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

ReferenceReference

Selective and orally bioavailable phenylglycine tissue factor/factor VIIa inhibitors., Zbinden KG, Obst-Sander U, Hilpert K, Kuhne H, Banner DW, Bohm HJ, Stahl M, Ackermann J, Alig L, Weber L, Wessel HP, Riederer MA, Tschopp TB, Lave T, Bioorg Med Chem Lett. 2005 Dec 1;15(23):5344-52. Epub 2005 Oct 4. PMID:16213138

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