1vqg: Difference between revisions

From Proteopedia
Jump to navigation Jump to search
No edit summary
No edit summary
Line 1: Line 1:
[[Image:1vqg.jpg|left|200px]]
{{Seed}}
[[Image:1vqg.png|left|200px]]


<!--
<!--
Line 9: Line 10:
{{STRUCTURE_1vqg|  PDB=1vqg  |  SCENE=  }}  
{{STRUCTURE_1vqg|  PDB=1vqg  |  SCENE=  }}  


'''GENE V PROTEIN MUTANT WITH ILE 47 REPLACED BY LEU 47 (I47L)'''
===GENE V PROTEIN MUTANT WITH ILE 47 REPLACED BY LEU 47 (I47L)===




==Overview==
<!--
The problem of rationally engineering protein molecules can be simplified where effects of mutations on protein function are additive. Crystal structures of single and double mutants in the hydrophobic core of gene V protein indicate that structural and functional effects of core mutations are additive when the regions structurally influenced by the mutations do not substantially overlap. These regions of influence can provide a simple basis for identifying sets of mutations that will show additive effects.
The line below this paragraph, {{ABSTRACT_PUBMED_8855252}}, adds the Publication Abstract to the page
(as it appears on PubMed at http://www.pubmed.gov), where 8855252 is the PubMed ID number.
-->
{{ABSTRACT_PUBMED_8855252}}


==About this Structure==
==About this Structure==
Line 27: Line 31:
[[Category: Gene v]]
[[Category: Gene v]]
[[Category: Mutant]]
[[Category: Mutant]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May  3 12:47:50 2008''
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 16:22:52 2008''

Revision as of 16:22, 29 July 2008

File:1vqg.png

Template:STRUCTURE 1vqg

GENE V PROTEIN MUTANT WITH ILE 47 REPLACED BY LEU 47 (I47L)GENE V PROTEIN MUTANT WITH ILE 47 REPLACED BY LEU 47 (I47L)

Template:ABSTRACT PUBMED 8855252

About this StructureAbout this Structure

1VQG is a Single protein structure of sequence from Enterobacteria phage f1. Full crystallographic information is available from OCA.

ReferenceReference

Potential use of additivity of mutational effects in simplifying protein engineering., Skinner MM, Terwilliger TC, Proc Natl Acad Sci U S A. 1996 Oct 1;93(20):10753-7. PMID:8855252

Page seeded by OCA on Tue Jul 29 16:22:52 2008

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA