Monocyte chemoattractant protein: Difference between revisions
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It exists as a monomer or a dimer, even though the homodimer form is preferred. | It exists as a monomer or a dimer, even though the homodimer form is preferred. | ||
The structure of the monomer is made of <scene name='72/721520/Ligand_binding_on_ccl2/2'>3 Beta sheets and 1 alpha helix</scene>. | The structure of the monomer is made of <scene name='72/721520/Ligand_binding_on_ccl2/2'>3 Beta sheets and 1 alpha helix</scene>. | ||
*'''MCP-3''' activates all types of | *'''MCP-1''' regulates migration and infiltration of monocytes/macrophages<ref>PMID:19441883</ref>. | ||
*'''MCP-3''' activates all types of leukocytes<ref>PMID:11781181</ref>. | |||
*'''MCP-4''' is a potent chemoattractant for monocytes and eosinophils and stimulates histamine release from basophils<ref>PMID:8955214</ref>. | *'''MCP-4''' is a potent chemoattractant for monocytes and eosinophils and stimulates histamine release from basophils<ref>PMID:8955214</ref>. | ||
== Ligands == | == Ligands == | ||