Catabolite control protein: Difference between revisions

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'''Catabolite control protein''' (CcpA) or '''glucose-resistant amylase regulator''' is a regulator of carbon metabolism in gram-positive bacteria.  When high concentrations of glucose-6 phosphate or fructose-1,6-diphosphate are present in the cell, they phosphorylate proteins HPr or Crh which interact with CcpA.  The latter binds to DNA operator to modulate transcription.<ref>PMID:16321938</ref>  
'''Catabolite control protein''' (CcpA) or '''glucose-resistant amylase regulator''' is a regulator of carbon metabolism in gram-positive bacteria.  When high concentrations of glucose-6 phosphate or fructose-1,6-diphosphate are present in the cell, they phosphorylate proteins HPr or Crh which interact with CcpA.  The latter binds to DNA operator to modulate transcription.<ref>PMID:16321938</ref>  
*'''CcpC''' Regulates the transcription of genes belonging to th TCA cycle<ref>PMID:1634645869</ref> .
*'''CcpC''' Regulates the transcription of genes belonging to the TCA cycle<ref>PMID:34645869</ref> .
*'''CcpE''' Regulates the transcription of genes belonging to the TCA cycle in ''Staphylococcus aureus''<ref>PMID:25193664</ref> .


== Structural highlights ==
== Structural highlights ==

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Michal Harel, Alexander Berchansky