MAP kinase phosphatase: Difference between revisions
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== Function == | == Function == | ||
'''MAP kinase phosphatase''' (MKP) or '''Dual specificity phosphatase''' (DUSP) are phosphatases which reverse the activation of MAP kinases by dephosphorylating tyrosine or threonine residues<ref>PMID:18922965</ref>.<br /> | '''MAP kinase phosphatase''' (MKP) or '''Dual specificity phosphatase''' (DUSP) are phosphatases which reverse the activation of MAP kinases by dephosphorylating tyrosine or threonine residues<ref>PMID:18922965</ref>.<br /> | ||
*'''MKP-2''' is essential in protection against intracellular infection<ref>PMID:21085614</ref>.<br /> | |||
*'''MKP-4''' and '''MKP-5''' are localized in the nucleus and cytosole<br /> | *'''MKP-4''' and '''MKP-5''' are localized in the nucleus and cytosole<br /> | ||
*'''MKP-6, MKP-7''' and '''MKP-3''' are localized in the nucleus<br /> | *'''MKP-6, MKP-7''' and '''MKP-3''' are localized in the nucleus<br /> | ||