Cyclin: Difference between revisions
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* '''CYCB1''' is essential for the control of the cell cycle at the G2/M (mitosis) transition.<br /> | * '''CYCB1''' is essential for the control of the cell cycle at the G2/M (mitosis) transition.<br /> | ||
* '''CYCC''' is active in the G0/G1 phase transition<ref>PMID:12910258</ref>.<br /> | * '''CYCC''' is active in the G0/G1 phase transition<ref>PMID:12910258</ref>.<br /> | ||
* '''CYCCCL1''' controls the phosphorylation of RNA polymerase II largest subunit and mRNA transcription <ref>PMID:8761664</ref><br /> | |||
* '''CYCD''' regulates the transition from G1 to S.<ref>PMID:15130482</ref><br /> | * '''CYCD''' regulates the transition from G1 to S.<ref>PMID:15130482</ref><br /> | ||
* '''CYCE''' and its CDK partner are key regulators of DNA synthesis and of mitosis.<ref>PMID:11907280</ref><br /> | * '''CYCE''' and its CDK partner are key regulators of DNA synthesis and of mitosis.<ref>PMID:11907280</ref><br /> | ||
* '''CYCF''' is the substrate recognition component of the Skp1-Cul1-F-box E3 ubiquitin ligase complex<ref>PMID:28652210</ref><br /> | |||
* '''CYCH''' is highly expressed in ovarian cancer<ref>PMID:32694938</ref><br /> | * '''CYCH''' is highly expressed in ovarian cancer<ref>PMID:32694938</ref><br /> | ||
* '''CYCK''' and its CDK12 partner regulate the expression of DNA-damage response genes and thus protect cells from genomic instability.<ref>PMID:22012619</ref><br /> | * '''CYCK''' and its CDK12 partner regulate the expression of DNA-damage response genes and thus protect cells from genomic instability.<ref>PMID:22012619</ref><br /> | ||