1sj0: Difference between revisions

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

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-[[Image:1sj0.gif|left|200px]]
+{{Seed}}
+[[Image:1sj0.png|left|200px]]
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 {{STRUCTURE_1sj0|  PDB=1sj0  |  SCENE=  }}
-'''Human Estrogen Receptor Alpha Ligand-binding Domain in Complex with the Antagonist Ligand 4-D'''
+===Human Estrogen Receptor Alpha Ligand-binding Domain in Complex with the Antagonist Ligand 4-D===
-==Overview==
+<!--
-The discovery and synthesis of dihydrobenzoxathiins as potent, ERalpha subtype selective ligands are described. The most active analogue, 4-D, was found to be 50-fold selective in a competitive binding assay and 100-fold selective in a transactivation assay in HEK-293 cells. The alpha selectivity was postulated to lie in the interaction of the sulfur atom of the benzoxathiin ring with the two discriminating residues in the binding pocket of the receptor isoforms.
+The line below this paragraph, {{ABSTRACT_PUBMED_15084115}}, adds the Publication Abstract to the page
+(as it appears on PubMed at http://www.pubmed.gov), where 15084115 is the PubMed ID number.
+-->
+{{ABSTRACT_PUBMED_15084115}}
 ==About this Structure==
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 [[Category: Nuclear receptor]]
 [[Category: Transcription factor]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May  3 08:45:34 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 03:12:20 2008''