9bc9: Difference between revisions

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'''Unreleased structure'''


The entry 9bc9 is ON HOLD  until Paper Publication
==Structure of KLHDC2 bound to SJ10278==
 
<StructureSection load='9bc9' size='340' side='right'caption='[[9bc9]], [[Resolution|resolution]] 1.91&Aring;' scene=''>
Authors:  
== Structural highlights ==
 
<table><tr><td colspan='2'>[[9bc9]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9BC9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9BC9 FirstGlance]. <br>
Description:  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.91&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A1APK:N-({2-[2-chloro-4-(methoxymethoxy)phenyl]-1,3-thiazol-4-yl}acetyl)glycine'>A1APK</scene>, <scene name='pdbligand=NCO:COBALT+HEXAMMINE(III)'>NCO</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9bc9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9bc9 OCA], [https://pdbe.org/9bc9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9bc9 RCSB], [https://www.ebi.ac.uk/pdbsum/9bc9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9bc9 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/KLDC2_HUMAN KLDC2_HUMAN] Represses CREB3-mediated transcription by interfering with CREB3-DNA binding.<ref>PMID:11384994</ref>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Chai SC]]
[[Category: Chen T]]
[[Category: Dharuman S]]
[[Category: Elledge SJ]]
[[Category: Gee CT]]
[[Category: Griffith E]]
[[Category: Harper JW]]
[[Category: Jayasinghe T]]
[[Category: King MT]]
[[Category: Lee C]]
[[Category: Lee HW]]
[[Category: Lee RE]]
[[Category: Miller DJ]]
[[Category: Ochoada J]]
[[Category: Paulo JA]]
[[Category: Ronnebaum J]]
[[Category: Schulman BA]]
[[Category: Scott DC]]
[[Category: Tangallapally R]]

Latest revision as of 11:14, 6 November 2024

Structure of KLHDC2 bound to SJ10278Structure of KLHDC2 bound to SJ10278

Structural highlights

9bc9 is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.91Å
Ligands:,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

KLDC2_HUMAN Represses CREB3-mediated transcription by interfering with CREB3-DNA binding.[1]

References

  1. ↑ Zhou HJ, Wong CM, Chen JH, Qiang BQ, Yuan JG, Jin DY. Inhibition of LZIP-mediated transcription through direct interaction with a novel host cell factor-like protein. J Biol Chem. 2001 Aug 3;276(31):28933-8. doi: 10.1074/jbc.M103893200. Epub 2001, May 30. PMID:11384994 doi:http://dx.doi.org/10.1074/jbc.M103893200

9bc9, resolution 1.91Å

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OCA
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