8xxh: Difference between revisions

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'''Unreleased structure'''


The entry 8xxh is ON HOLD  until Paper Publication
==Structure of CXCR2 bound to CXCL2 (CXCR2-CXCL2-Go Full map)==
 
<StructureSection load='8xxh' size='340' side='right'caption='[[8xxh]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
Authors: Sano, F.K., Saha, S., Sharma, S., Ganguly, M., Shihoya, W., Nureki, O., Shukla, A.K., Banerjee, R.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[8xxh]] is a 7 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8XXH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8XXH FirstGlance]. <br>
Description: Structure of CXCR2 bound to CXCL2 (CXCR2-CXCL2-Go Full map)
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8xxh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8xxh OCA], [https://pdbe.org/8xxh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8xxh RCSB], [https://www.ebi.ac.uk/pdbsum/8xxh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8xxh ProSAT]</span></td></tr>
[[Category: Ganguly, M]]
</table>
[[Category: Sharma, S]]
== Function ==
[[Category: Sano, F.K]]
[https://www.uniprot.org/uniprot/GBB1_HUMAN GBB1_HUMAN] Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.<ref>PMID:18611381</ref>
[[Category: Saha, S]]
== References ==
[[Category: Shukla, A.K]]
<references/>
[[Category: Banerjee, R]]
__TOC__
[[Category: Shihoya, W]]
</StructureSection>
[[Category: Nureki, O]]
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Banerjee R]]
[[Category: Ganguly M]]
[[Category: Nureki O]]
[[Category: Saha S]]
[[Category: Sano FK]]
[[Category: Sharma S]]
[[Category: Shihoya W]]
[[Category: Shukla AK]]

Latest revision as of 09:14, 15 January 2025

Structure of CXCR2 bound to CXCL2 (CXCR2-CXCL2-Go Full map)Structure of CXCR2 bound to CXCL2 (CXCR2-CXCL2-Go Full map)

Structural highlights

8xxh is a 7 chain structure with sequence from Homo sapiens and Mus musculus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:Electron Microscopy, Resolution 2.8Å
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

GBB1_HUMAN Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.[1]

References

  1. Johnston CA, Kimple AJ, Giguere PM, Siderovski DP. Structure of the parathyroid hormone receptor C terminus bound to the G-protein dimer Gbeta1gamma2. Structure. 2008 Jul;16(7):1086-94. PMID:18611381 doi:http://dx.doi.org/10.1016/j.str.2008.04.010

8xxh, resolution 2.80Å

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OCA