1saf: Difference between revisions

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-[[Image:1saf.gif|left|200px]]
+{{Seed}}
+[[Image:1saf.png|left|200px]]
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 {{STRUCTURE_1saf|  PDB=1saf  |  SCENE=  }}
-'''HIGH RESOLUTION SOLUTION NMR STRUCTURE OF THE OLIGOMERIZATION DOMAIN OF P53 BY MULTI-DIMENSIONAL NMR (SAD STRUCTURES)'''
+===HIGH RESOLUTION SOLUTION NMR STRUCTURE OF THE OLIGOMERIZATION DOMAIN OF P53 BY MULTI-DIMENSIONAL NMR (SAD STRUCTURES)===
-==Overview==
+<!--
-The NMR solution structure of the oligomerization domain of the tumour suppressor p53 (residues 319-360) has been refined. The structure comprises a dimer of dimers, oriented in an approximately orthogonal manner. The present structure determination is based on 4,472 experimental NMR restraints which represents a three and half fold increase over our previous work in the number of NOE restraints at the tetramerization interface. A comparison with the recently solved 1.7 A resolution X-ray structure shows that the structures are very similar and that the average angular root-mean-square difference in the interhelical angles is about 1 degree. The results of recent extensive mutagenesis data and the possible effects of mutations which have been identified in human cancers are discussed in the light of the present structure.
+The line below this paragraph, {{ABSTRACT_PUBMED_7796267}}, adds the Publication Abstract to the page
+(as it appears on PubMed at http://www.pubmed.gov), where 7796267 is the PubMed ID number.
+-->
+{{ABSTRACT_PUBMED_7796267}}
 ==About this Structure==
-SAF is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SAF OCA].
+SAF is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SAF OCA].
 ==Reference==
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 [[Category: Omichinski, J G.]]
 [[Category: Anti-oncogene]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May  3 08:28:58 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 11:28:49 2008''