8iyh: Difference between revisions

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'''Unreleased structure'''


The entry 8iyh is ON HOLD  until Paper Publication
==Structure of MK6892-GPR109A-G-protein complex==
 
<StructureSection load='8iyh' size='340' side='right'caption='[[8iyh]], [[Resolution|resolution]] 3.30&Aring;' scene=''>
Authors: Yadav, M.K., Sarma, P., Chami, M., Banerjee, R., Shukla, A.K.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[8iyh]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8IYH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8IYH FirstGlance]. <br>
Description: Structure of MK6892-GPR109A-G-protein complex
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.3&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FI7:2-[[2,2-dimethyl-3-[3-(5-oxidanylpyridin-2-yl)-1,2,4-oxadiazol-5-yl]propanoyl]amino]cyclohexene-1-carboxylic+acid'>FI7</scene></td></tr>
[[Category: Chami, M]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8iyh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8iyh OCA], [https://pdbe.org/8iyh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8iyh RCSB], [https://www.ebi.ac.uk/pdbsum/8iyh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8iyh ProSAT]</span></td></tr>
[[Category: Shukla, A.K]]
</table>
[[Category: Yadav, M.K]]
== Function ==
[[Category: Sarma, P]]
[https://www.uniprot.org/uniprot/GBB1_HUMAN GBB1_HUMAN] Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.<ref>PMID:18611381</ref>
[[Category: Banerjee, R]]
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Banerjee R]]
[[Category: Chami M]]
[[Category: Sarma P]]
[[Category: Shukla AK]]
[[Category: Yadav MK]]

Revision as of 15:05, 6 March 2024

Structure of MK6892-GPR109A-G-protein complexStructure of MK6892-GPR109A-G-protein complex

Structural highlights

8iyh is a 5 chain structure with sequence from Homo sapiens and Mus musculus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:Electron Microscopy, Resolution 3.3Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

GBB1_HUMAN Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.[1]

References

  1. ↑ Johnston CA, Kimple AJ, Giguere PM, Siderovski DP. Structure of the parathyroid hormone receptor C terminus bound to the G-protein dimer Gbeta1gamma2. Structure. 2008 Jul;16(7):1086-94. PMID:18611381 doi:http://dx.doi.org/10.1016/j.str.2008.04.010

8iyh, resolution 3.30Å

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OCA
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