1pqs: Difference between revisions

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-[[Image:1pqs.gif|left|200px]]
+{{Seed}}
+[[Image:1pqs.png|left|200px]]
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 {{STRUCTURE_1pqs|  PDB=1pqs  |  SCENE=  }}
-'''Solution structure of the C-terminal OPCA domain of yCdc24p'''
+===Solution structure of the C-terminal OPCA domain of yCdc24p===
-==Overview==
+<!--
-Phox and Bem1 (PB1) domains mediate protein-protein interactions via the formation of homo- or hetero-dimers. The C-terminal PB1 domain of yeast cell division cycle 24 (CDC24p), a guanine-nucleotide exchange factor involved in cell polarity establishment, is known to interact with the PB1 domain occurring in bud emergence MSB1 interacting 1 (BEM1p) during the regulation of the yeast budding process via its OPR/PC/AID (OPCA) motif. Here, we present the structure of an N-terminally truncated version of the Sc CDC24p PB1 domain. It shows a different topology of the beta-sheet than the long form. However, the C-terminal part of the structure shows the conserved PB1 domain features including the OPCA motif with a slight rearrangement of helix alpha1. Residues which are important for the heterodimerization with BEM1p are structurally preserved.
+The line below this paragraph, {{ABSTRACT_PUBMED_15961083}}, adds the Publication Abstract to the page
+(as it appears on PubMed at http://www.pubmed.gov), where 15961083 is the PubMed ID number.
+-->
+{{ABSTRACT_PUBMED_15961083}}
 ==About this Structure==
-PQS is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PQS OCA].
+PQS is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PQS OCA].
 ==Reference==
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 [[Category: Wahl, M.]]
 [[Category: Alpha and beta protein]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May  3 05:22:55 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 15:09:29 2008''