8hoc: Difference between revisions

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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8hoc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8hoc OCA], [https://pdbe.org/8hoc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8hoc RCSB], [https://www.ebi.ac.uk/pdbsum/8hoc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8hoc ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8hoc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8hoc OCA], [https://pdbe.org/8hoc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8hoc RCSB], [https://www.ebi.ac.uk/pdbsum/8hoc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8hoc ProSAT]</span></td></tr>
</table>
</table>
== Function ==
 
[https://www.uniprot.org/uniprot/GNAI1_HUMAN GNAI1_HUMAN] Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(i) proteins are involved in hormonal regulation of adenylate cyclase: they inhibit the cyclase in response to beta-adrenergic stimuli. The inactive GDP-bound form prevents the association of RGS14 with centrosomes and is required for the translocation of RGS14 from the cytoplasm to the plasma membrane. May play a role in cell division.<ref>PMID:17635935</ref> <ref>PMID:17264214</ref>
==See Also==
== References ==
*[[Transducin 3D structures|Transducin 3D structures]]
<references/>
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</StructureSection>

Latest revision as of 12:41, 17 October 2024

Cryo-EM structure of ligand histamine-bound Histamine H4 receptor Gi complexCryo-EM structure of ligand histamine-bound Histamine H4 receptor Gi complex

Structural highlights

8hoc is a 5 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:Electron Microscopy, Resolution 3Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

See Also

8hoc, resolution 3.00Å

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OCA