8wnf: Difference between revisions

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-'''Unreleased structure'''
-The entry 8wnf is ON HOLD  until Paper Publication
+==Crystal structure of H. pylori isoleucyl-tRNA synthetase (HpIleRS) in apo form==
+<StructureSection load='8wnf' size='340' side='right'caption='[[8wnf]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
-Authors: Guo, Y., Li, S., Zhang, T.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[8wnf]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Helicobacter_pylori Helicobacter pylori]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8WNF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8WNF FirstGlance]. <br>
-Description: Crystal structures of H. pylori isoleucyl-tRNA synthetase (HpIleRS) in apo form
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
-[[Category: Unreleased Structures]]
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-[[Category: Li, S]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8wnf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8wnf OCA], [https://pdbe.org/8wnf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8wnf RCSB], [https://www.ebi.ac.uk/pdbsum/8wnf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8wnf ProSAT]</span></td></tr>
-[[Category: Zhang, T]]
+</table>
-[[Category: Guo, Y]]
+== Function ==
+[https://www.uniprot.org/uniprot/A0A2J9KLI1_HELPX A0A2J9KLI1_HELPX] Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).[ARBA:ARBA00025217][HAMAP-Rule:MF_02002]
+__TOC__
+</StructureSection>
+[[Category: Helicobacter pylori]]
+[[Category: Large Structures]]
+[[Category: Guo Y]]
+[[Category: Li S]]
+[[Category: Zhang T]]