Osimertinib: Difference between revisions

From Proteopedia
Jump to navigation Jump to search
No edit summary
No edit summary
Line 3: Line 3:


<scene name='99/999451/Overall/1'>Crystal Structure of EGFR(L858R/T790M/C797S) in complex with Osimertinib</scene> ([[6lud]]).
<scene name='99/999451/Overall/1'>Crystal Structure of EGFR(L858R/T790M/C797S) in complex with Osimertinib</scene> ([[6lud]]).
<scene name='99/999451/Binding_site/1'>Osimertinib binding site</scene>.


</StructureSection>
</StructureSection>
== References ==
== References ==
<references/>
<references/>

Revision as of 16:11, 10 October 2023

Osimertinib, sold under the brand name Tagrisso,[1] is a medication used to treat non-small-cell lung carcinomas with specific mutations.[2][3] It is a third-generation epidermal growth factor receptor tyrosine kinase inhibitor (see Receptor tyrosine kinases). See also Osimertinib.

(6lud).

.


Caption for this structure

Drag the structure with the mouse to rotate

ReferencesReferences

  1. "Proposed INN: List 113" (PDF). International Nonproprietary Names for Pharmaceutical Substances (INN). 29 (2): 285. 2015. Archived (PDF) from the original on 28 April 2017. Retrieved 16 November 2015
  2. Ayeni D, Politi K, Goldberg SB. Emerging Agents and New Mutations in EGFR-Mutant Lung Cancer. Clin Cancer Res. 2015 Sep 1;21(17):3818-20. PMID:26169963 doi:10.1158/1078-0432.CCR-15-1211
  3. Tan CS, Gilligan D, Pacey S. Treatment approaches for EGFR-inhibitor-resistant patients with non-small-cell lung cancer. Lancet Oncol. 2015 Sep;16(9):e447-e459. PMID:26370354 doi:10.1016/S1470-2045(15)00246-6

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

Alexander Berchansky, Michal Harel