1mms: Difference between revisions

Revision as of 00:24, 3 July 2008

This article has been automatically seeded. Changes to this page should pertain to the PDB entry only and not to the protein or biomolecule in general.

File:1mms.png

Template:STRUCTURE 1mms

CRYSTAL STRUCTURE OF THE RIBOSOMAL PROTEIN L11-RNA COMPLEXCRYSTAL STRUCTURE OF THE RIBOSOMAL PROTEIN L11-RNA COMPLEX

Template:ABSTRACT PUBMED 10338213

About this StructureAbout this Structure

1MMS is a Single protein structure of sequence from Thermotoga maritima. Full crystallographic information is available from OCA.

ReferenceReference

A detailed view of a ribosomal active site: the structure of the L11-RNA complex., Wimberly BT, Guymon R, McCutcheon JP, White SW, Ramakrishnan V, Cell. 1999 May 14;97(4):491-502. PMID:10338213

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Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

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-'''CRYSTAL STRUCTURE OF THE RIBOSOMAL PROTEIN L11-RNA COMPLEX'''
+===CRYSTAL STRUCTURE OF THE RIBOSOMAL PROTEIN L11-RNA COMPLEX===
-==Overview==
+<!--
-We report the crystal structure of a 58 nucleotide fragment of 23S ribosomal RNA bound to ribosomal protein L11. This highly conserved ribonucleoprotein domain is the target for the thiostrepton family of antibiotics that disrupt elongation factor function. The highly compact RNA has both familiar and novel structural motifs. While the C-terminal domain of L11 binds RNA tightly, the N-terminal domain makes only limited contacts with RNA and is proposed to function as a switch that reversibly associates with an adjacent region of RNA. The sites of mutations conferring resistance to thiostrepton and micrococcin line a narrow cleft between the RNA and the N-terminal domain. These antibiotics are proposed to bind in this cleft, locking the putative switch and interfering with the function of elongation factors.
+The line below this paragraph, {{ABSTRACT_PUBMED_10338213}}, adds the Publication Abstract to the page
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+{{ABSTRACT_PUBMED_10338213}}
 ==About this Structure==
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 [[Category: Thiostrepton]]
 [[Category: Translocation]]
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