8q4m: Difference between revisions

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'''Unreleased structure'''


The entry 8q4m is ON HOLD  until 2025-08-07
==Crystal structure of YTHDC1 in complex with Compound 25 (ZA_349)==
 
<StructureSection load='8q4m' size='340' side='right'caption='[[8q4m]], [[Resolution|resolution]] 1.43&Aring;' scene=''>
Authors: Bedi, R.K., Zalesak, F., Caflisch, A.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[8q4m]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8Q4M OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8Q4M FirstGlance]. <br>
Description: Crystal structure of YTHDC1 in complex with Compound 25 (ZA_349)
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.43&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=J9B:2-chloranyl-9-[(3-chlorophenyl)methyl]-~{N}-methyl-purin-6-amine'>J9B</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
[[Category: Caflisch, A]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8q4m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8q4m OCA], [https://pdbe.org/8q4m PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8q4m RCSB], [https://www.ebi.ac.uk/pdbsum/8q4m PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8q4m ProSAT]</span></td></tr>
[[Category: Bedi, R.K]]
</table>
[[Category: Zalesak, F]]
== Function ==
[https://www.uniprot.org/uniprot/YTDC1_HUMAN YTDC1_HUMAN] RNA-binding protein that regulates alternative splice site selection.<ref>PMID:20167602</ref>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Bedi RK]]
[[Category: Caflisch A]]
[[Category: Zalesak F]]

Latest revision as of 11:04, 6 December 2023

Crystal structure of YTHDC1 in complex with Compound 25 (ZA_349)Crystal structure of YTHDC1 in complex with Compound 25 (ZA_349)

Structural highlights

8q4m is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.43Å
Ligands:,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

YTDC1_HUMAN RNA-binding protein that regulates alternative splice site selection.[1]

References

  1. ↑ Zhang Z, Theler D, Kaminska KH, Hiller M, de la Grange P, Pudimat R, Rafalska I, Heinrich B, Bujnicki JM, Allain FH, Stamm S. The YTH domain is a novel RNA binding domain. J Biol Chem. 2010 May 7;285(19):14701-10. doi: 10.1074/jbc.M110.104711. Epub 2010, Feb 18. PMID:20167602 doi:http://dx.doi.org/10.1074/jbc.M110.104711

8q4m, resolution 1.43Å

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OCA
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