1m2e: Difference between revisions

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-[[Image:1m2e.jpg|left|200px]]
+{{Seed}}
+[[Image:1m2e.png|left|200px]]
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 {{STRUCTURE_1m2e|  PDB=1m2e  |  SCENE=  }}
-'''Solution structure of the N-terminal domain of Synechococcus elongatus KaiA (KaiA135N); Average minimized structure.'''
+===Solution structure of the N-terminal domain of Synechococcus elongatus KaiA (KaiA135N); Average minimized structure.===
-==Overview==
+<!--
-In the cyanobacterium Synechococcus elongatus (PCC 7942) the proteins KaiA, KaiB, and KaiC are required for circadian clock function. We deduced a circadian clock function for KaiA from a combination of biochemical and structural data. Both KaiA and its isolated carboxyl-terminal domain (KaiA180C) stimulated KaiC autophosphorylation and facilitated attenuation of KaiC autophosphorylation by KaiB. An amino-terminal domain (KaiA135N) had no function in the autophosphorylation assay. NMR structure determination showed that KaiA135N is a pseudo-receiver domain. We propose that this pseudo-receiver is a timing input-device that regulates KaiA stimulation of KaiC autophosphorylation, which in turn is essential for circadian timekeeping.
+The line below this paragraph, {{ABSTRACT_PUBMED_12438647}}, adds the Publication Abstract to the page
+(as it appears on PubMed at http://www.pubmed.gov), where 12438647 is the PubMed ID number.
+-->
+{{ABSTRACT_PUBMED_12438647}}
 ==About this Structure==
-M2E is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Synechococcus_elongatus Synechococcus elongatus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1M2E OCA].
+M2E is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Synechococcus_elongatus Synechococcus elongatus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1M2E OCA].
 ==Reference==
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 [[Category: Williams, S B.]]
 [[Category: Alpha-beta-alpha sandwich]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May  3 00:33:03 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul  2 23:04:21 2008''