5e4e: Difference between revisions

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OCA

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 <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5e4e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5e4e OCA], [https://pdbe.org/5e4e PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5e4e RCSB], [https://www.ebi.ac.uk/pdbsum/5e4e PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5e4e ProSAT]</span></td></tr>
 </table>
-== Disease ==
-[https://www.uniprot.org/uniprot/IL13_HUMAN IL13_HUMAN] Defects in IL13 may be a cause of susceptibility to allergic rhinitis (ALRH) [MIM:[https://omim.org/entry/607154 607154]. Allergic rhinitis is a common disease of complex inheritance and is characterized by mucosal inflammation caused by allergen exposure.
 == Function ==
-[https://www.uniprot.org/uniprot/IL13_HUMAN IL13_HUMAN] Cytokine. Inhibits inflammatory cytokine production. Synergizes with IL2 in regulating interferon-gamma synthesis. May be critical in regulating inflammatory and immune responses.
+[https://www.uniprot.org/uniprot/I13R1_HUMAN I13R1_HUMAN] Binds with low affinity to interleukin-13 (IL13). Together with IL4RA can form a functional receptor for IL13. Also serves as an alternate accessory protein to the common cytokine receptor gamma chain for interleukin-4 (IL4) signaling, but cannot replace the function of IL2RG in allowing enhanced interleukin-2 (IL2) binding activity.
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 == Publication Abstract from PubMed ==