1kxl: Difference between revisions

Revision as of 11:14, 2 July 2008

This article has been automatically seeded. Changes to this page should pertain to the PDB entry only and not to the protein or biomolecule in general.

File:1kxl.png

Template:STRUCTURE 1kxl

Solution Structure of the Cdc13 DNA-binding Domain in a Complex with Single-Stranded Telomeric DNA (DNA structure not modeled)Solution Structure of the Cdc13 DNA-binding Domain in a Complex with Single-Stranded Telomeric DNA (DNA structure not modeled)

Template:ABSTRACT PUBMED 11935027

About this StructureAbout this Structure

1KXL is a Single protein structure of sequence from Saccharomyces cerevisiae. Full experimental information is available from OCA.

ReferenceReference

Conserved structure for single-stranded telomeric DNA recognition., Mitton-Fry RM, Anderson EM, Hughes TR, Lundblad V, Wuttke DS, Science. 2002 Apr 5;296(5565):145-7. PMID:11935027

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Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

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-'''Solution Structure of the Cdc13 DNA-binding Domain in a Complex with Single-Stranded Telomeric DNA (DNA structure not modeled)'''
+===Solution Structure of the Cdc13 DNA-binding Domain in a Complex with Single-Stranded Telomeric DNA (DNA structure not modeled)===
-==Overview==
+<!--
-The essential Cdc13 protein in the yeast Saccharomyces cerevisiae is a single-stranded telomeric DNA binding protein required for chromosome end protection and telomere replication. Here we report the solution structure of the Cdc13 DNA binding domain in complex with telomeric DNA. The structure reveals the use of a single OB (oligonucleotide/oligosaccharide binding) fold augmented by an unusually large loop for DNA recognition. This OB fold is structurally similar to OB folds found in the ciliated protozoan telomere end-binding protein, although no sequence similarity is apparent between them. The common usage of an OB fold for telomeric DNA interaction demonstrates conservation of end-protection mechanisms among eukaryotes.
+The line below this paragraph, {{ABSTRACT_PUBMED_11935027}}, adds the Publication Abstract to the page
+(as it appears on PubMed at http://www.pubmed.gov), where 11935027 is the PubMed ID number.
+-->
+{{ABSTRACT_PUBMED_11935027}}
 ==About this Structure==
-KXL is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KXL OCA].
+KXL is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KXL OCA].
 ==Reference==
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 [[Category: Single-stranded dna]]
 [[Category: Telomere]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May  2 23:17:43 2008''
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