8sep: Difference between revisions

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-'''Unreleased structure'''
-The entry 8sep is ON HOLD  until Paper Publication
+==Cryo-EM Structure of RyR1 + ADP==
+<StructureSection load='8sep' size='340' side='right'caption='[[8sep]], [[Resolution|resolution]] 3.57&Aring;' scene=''>
-Authors:
+== Structural highlights ==
+<table><tr><td colspan='2'>[[8sep]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8SEP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8SEP FirstGlance]. <br>
-Description:
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8sep FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8sep OCA], [https://pdbe.org/8sep PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8sep RCSB], [https://www.ebi.ac.uk/pdbsum/8sep PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8sep ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/GST26_SCHJA GST26_SCHJA] Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.  GST isoenzymes appear to play a central role in the parasite detoxification system. Other functions are also suspected including a role in increasing the solubility of haematin in the parasite gut.[https://www.uniprot.org/uniprot/FKB1B_HUMAN FKB1B_HUMAN] Has the potential to contribute to the immunosuppressive and toxic effects of FK506 and rapamycin. PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
+__TOC__
+</StructureSection>
+[[Category: Homo sapiens]]
+[[Category: Large Structures]]
+[[Category: Oryctolagus cuniculus]]
+[[Category: Berezuk AM]]
+[[Category: Cholak S]]
+[[Category: Haji-Ghassemi O]]
+[[Category: Saville JW]]
+[[Category: Subramaniam S]]
+[[Category: Tuttle KS]]
+[[Category: Van Petegem F]]
+[[Category: Zhu X]]