8sib: Difference between revisions

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-'''Unreleased structure'''
-The entry 8sib is ON HOLD  until Paper Publication
+==Cryo-EM structure of TRPM7 MHR1-3 domain==
+<StructureSection load='8sib' size='340' side='right'caption='[[8sib]], [[Resolution|resolution]] 2.62&Aring;' scene=''>
-Authors:
+== Structural highlights ==
+<table><tr><td colspan='2'>[[8sib]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8SIB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8SIB FirstGlance]. <br>
-Description:
+</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8sib FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8sib OCA], [https://pdbe.org/8sib PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8sib RCSB], [https://www.ebi.ac.uk/pdbsum/8sib PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8sib ProSAT]</span></td></tr>
-[[Category: Unreleased Structures]]
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/TRPM7_MOUSE TRPM7_MOUSE] Essential ion channel and serine/threonine-protein kinase. Divalent cation channel permeable to calcium and magnesium. Has a central role in magnesium ion homeostasis and in the regulation of anoxic neuronal cell death. The kinase activity is essential for the channel function. May be involved in a fundamental process that adjusts plasma membrane divalent cation fluxes according to the metabolic state of the cell. Phosphorylates annexin A1 (ANXA1).<ref>PMID:11385574</ref>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Large Structures]]
+[[Category: Mus musculus]]
+[[Category: Nadezhdin KD]]
+[[Category: Neuberger A]]
+[[Category: Sobolevsky AI]]