Band 3: Difference between revisions

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Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

Ann Taylor, Michal Harel

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 ==Band 3==
-<StructureSection load='4yzf' size='340' side='right' caption='Band 3 dimer' scene=''>
+<StructureSection load='7rtm' size='340' side='right' caption='Band 3 dimer' scene=''>
-Anion exchanger 1 (AE1), also known as band 3 or SLC4A1, exchanges chloride and bicarbonate across the red blood cell membrane, assisting in removing carbon dioxide from tissues. It also anchors the membrane skeleton <ref>PMID:34669510</ref>.
+Anion exchanger 1 (AE1), also known as band 3 or SLC4A1, exchanges chloride and bicarbonate across the red blood cell membrane, assisting in removing carbon dioxide from tissues. It also anchors the membrane skeleton <ref>PMID:34669510</ref>. Band 3's name comes from its appearance as the third major band on SDS-PAGE of red blood cell membrane proteins <ref>PMID: 4326772</ref>.
+Its function has been studied for more than 150 years; even so, the first complete structure was not published until 2015 <ref>PMID: 26542571</ref>, and the first crystals grown without addition of an antibody were grown on the International Space Station <ref> PMID: 30118660</ref>.
 == Structural highlights ==
-This is a sample scene created with SAT to <scene name="/12/3456/Sample/1">color</scene> by Group, and another to make <scene name="/12/3456/Sample/2">a transparent representation</scene> of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes.
+Band 3 functions as a <scene name='96/962946/Dimer_inside_outside/1'>dimer</scene>.  Each monomer contains fourteen transmembrane segments, as well as an intracellular domain that plays a gating role and a small extracellular domain.
 </StructureSection>
 == References ==
 <references/>