Citric Acid Cycle: Difference between revisions
No edit summary |
No edit summary |
||
Line 6: | Line 6: | ||
*[[Krebs cycle overview]] | *[[Krebs cycle overview]] | ||
*[[Krebs cycle reactions]] | *[[Krebs cycle reactions]] | ||
*[[Major metabolic pathways converging on the citric acid cycle]] | |||
*[[Citric acid cycle intermediates serve as substrates for biosynthetic processes]] | |||
The [[Citric Acid Cycle]] (tricarboxylic acid cycle) is a series of enzyme catalyzed reactions which are critical in cellular respiration. Under oxidative conditions, pyruvate continues to be metabolized through the tricarboxylic acid cycle. In this cycle, Acetyl-CoA, a byproduct of [[glycolysis]], along with various cofactors, are broken down into carbon dioxide, water, and energy in the form of GTP and NADH. | The [[Citric Acid Cycle]] (tricarboxylic acid cycle) is a series of enzyme catalyzed reactions which are critical in cellular respiration. Under oxidative conditions, pyruvate continues to be metabolized through the tricarboxylic acid cycle. In this cycle, Acetyl-CoA, a byproduct of [[glycolysis]], along with various cofactors, are broken down into carbon dioxide, water, and energy in the form of GTP and NADH. | ||
Line 49: | Line 51: | ||
*[[2-Oxoglutarate Dehydrogenase]] | *[[2-Oxoglutarate Dehydrogenase]] | ||
*Step 5 = [[Krebs cycle step 4]] | *Step 5 = [[Krebs cycle step 4]] | ||
5C α-Ketoglutarate => <scene name='43/430893/Cv/9'>Succinyl-CoA</scene> 4C chain (CoA excluded) | 5C α-Ketoglutarate => <scene name='43/430893/Cv/9'>Succinyl-CoA</scene> 4C chain (CoA excluded). The succinyl-CoA formed during [[Beta oxidationcan]] also can enter the [[Citric Acid Cycle]]. | ||
'''Step 6 - Substrate-level phosphorylation - Succinyl-CoA synthetase''' | '''Step 6 - Substrate-level phosphorylation - Succinyl-CoA synthetase''' |