4br1: Difference between revisions

<table><tr><td colspan='2'>[[4br1]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BR1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4BR1 FirstGlance]. <br>

</td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Triose-phosphate_isomerase Triose-phosphate isomerase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.3.1.1 5.3.1.1] </span></td></tr>

[[https://www.uniprot.org/uniprot/TPIS_HUMAN TPIS_HUMAN]] Defects in TPI1 are the cause of triosephosphate isomerase deficiency (TPI deficiency) [MIM:[https://omim.org/entry/190450 190450]]. TPI deficiency is an autosomal recessive disorder. It is the most severe clinical disorder of glycolysis. It is associated with neonatal jaundice, chronic hemolytic anemia, progressive neuromuscular dysfunction, cardiomyopathy and increased susceptibility to infection.  

[[Category: Human]]

[[Category: Castillo-Villanueva, A]]

[[Category: DeLaMora-DeLaMora, I]]

[[Category: Enriquez-Flores, S]]

[[Category: Garcia-Torres, I]]

[[Category: Gomez-Manzo, S]]

[[Category: Hernandez-Alcantara, G]]

[[Category: Lopez-Velazquez, G]]

[[Category: Marcial-Quino, J]]

[[Category: Mendez, S T]]

[[Category: Mendoza-Hernandez, G]]

[[Category: Oria-Hernandez, J]]

[[Category: Reyes-Vivas, H]]

[[Category: Torres-Arroyo, A]]

[[Category: Torres-Larios, A]]

[[Category: Protease degradation]]