7fi9: Difference between revisions
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==== | ==Crystal structure of human MICA mutants in complex with natural killer cell receptor NKG2D== | ||
<StructureSection load='7fi9' size='340' side='right'caption='[[7fi9]]' scene=''> | <StructureSection load='7fi9' size='340' side='right'caption='[[7fi9]], [[Resolution|resolution]] 2.16Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br> | <table><tr><td colspan='2'>[[7fi9]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7FI9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7FI9 FirstGlance]. <br> | ||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7fi9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7fi9 OCA], [https://pdbe.org/7fi9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7fi9 RCSB], [https://www.ebi.ac.uk/pdbsum/7fi9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7fi9 ProSAT]</span></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7fi9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7fi9 OCA], [https://pdbe.org/7fi9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7fi9 RCSB], [https://www.ebi.ac.uk/pdbsum/7fi9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7fi9 ProSAT]</span></td></tr> | |||
</table> | </table> | ||
== Function == | |||
[[https://www.uniprot.org/uniprot/NKG2D_HUMAN NKG2D_HUMAN]] Receptor for MICA, MICB, ULBP1, ULBP2, ULBP3 (ULBP2>ULBP1>ULBP3) and ULBP4. Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. Involved in the immune surveillance exerted by T- and B-lymphocytes. | |||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: | [[Category: Cai W]] | ||
[[Category: Li Y]] | |||
[[Category: Liu J]] | |||
[[Category: Peng S]] | |||
[[Category: Tian Y]] | |||
[[Category: Xu T]] | |||