8e11: Difference between revisions

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OCA

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-'''Unreleased structure'''
-The entry 8e11 is ON HOLD
+==Structure of mouse DNA polymerase Beta (PolB) mutant==
+<StructureSection load='8e11' size='340' side='right'caption='[[8e11]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
-Authors:
+== Structural highlights ==
+<table><tr><td colspan='2'>[[8e11]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8E11 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8E11 FirstGlance]. <br>
-Description:
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=MLA:MALONIC+ACID'>MLA</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8e11 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8e11 OCA], [https://pdbe.org/8e11 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8e11 RCSB], [https://www.ebi.ac.uk/pdbsum/8e11 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8e11 ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/DPOLB_MOUSE DPOLB_MOUSE] Repair polymerase that plays a key role in base-excision repair. Has 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity that removes the 5' sugar phosphate and also acts as a DNA polymerase that adds one nucleotide to the 3' end of the arising single-nucleotide gap. Conducts 'gap-filling' DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases (By similarity).
+__TOC__
+</StructureSection>
+[[Category: Large Structures]]
+[[Category: Mus musculus]]
+[[Category: Prakash A]]
+[[Category: Sharma N]]
+[[Category: Thompson MK]]