8dfl: Difference between revisions
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==== | ==Structure of human Kv1.3 with A0194009G09 nanobodies (alternate conformation)== | ||
<StructureSection load='8dfl' size='340' side='right'caption='[[8dfl]]' scene=''> | <StructureSection load='8dfl' size='340' side='right'caption='[[8dfl]], [[Resolution|resolution]] 3.25Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br> | <table><tr><td colspan='2'>[[8dfl]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Aequorea_victoria Aequorea victoria], [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Lama_glama Lama glama]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8DFL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8DFL FirstGlance]. <br> | ||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8dfl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8dfl OCA], [https://pdbe.org/8dfl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8dfl RCSB], [https://www.ebi.ac.uk/pdbsum/8dfl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8dfl ProSAT]</span></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=K:POTASSIUM+ION'>K</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8dfl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8dfl OCA], [https://pdbe.org/8dfl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8dfl RCSB], [https://www.ebi.ac.uk/pdbsum/8dfl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8dfl ProSAT]</span></td></tr> | |||
</table> | </table> | ||
== Function == | |||
[[https://www.uniprot.org/uniprot/KCNA3_HUMAN KCNA3_HUMAN]] Mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient.[[https://www.uniprot.org/uniprot/GFP_AEQVI GFP_AEQVI]] Energy-transfer acceptor. Its role is to transduce the blue chemiluminescence of the protein aequorin into green fluorescent light by energy transfer. Fluoresces in vivo upon receiving energy from the Ca(2+)-activated photoprotein aequorin. | |||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Aequorea victoria]] | |||
[[Category: Homo sapiens]] | |||
[[Category: Lama glama]] | |||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: | [[Category: Meyerson JR]] | ||
[[Category: Selvakumar P]] | |||