Peregrin: Difference between revisions
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Mutations within the gene itself have been associated with neurological disorders and widespread reduced histone acetylation <ref name="Yan" />. | Mutations within the gene itself have been associated with neurological disorders and widespread reduced histone acetylation <ref name="Yan" />. | ||
==Peregrin PDB structures== | |||
* Peregrin; Domains – PZP 274-450; bromodomain 626-740; PWWP 1079-1207 | |||
**[[3l42]] – hBRPF1 PWWP domain - human<br /> | |||
**[[5erc]] – hBRPF1 PZP domain<br /> | |||
**[[4lc2]], [[7c4i]] – hBRPF1 bromodomain <br /> | |||
**[[2d9e]] – hBRPF1 bromodomain - NMR<br /> | |||
* Peregrin complexes | |||
**[[5ewv]], [[5eww]], [[5c89]], [[5g4r]], [[5g4s]], [[5em3]], [[5ev9]], [[5eva]], [[5ewh]], [[5c85]], [[5c87]], [[5d7x]], [[5dy7]], [[5d7a]], [[5dyc]], [[5e3d]], [[5e3g]], [[5epr]], [[5eps]], [[5eq1]], [[5etb]], [[5etd]], [[5ewc]], [[5ewd]], [[5ffy]], [[5c7n]], [[4uye]], [[5dya]] – hBRPF1 bromodomain + ligand <br /> | |||
**[[5ffv]], [[5ffw]], [[4qyd]], [[4qyl]] – hBRPF1 bromodomain + histone peptide<br /> | |||
**[[2rs9]] – hBRPF1 bromodomain + histone peptide - NMR<br /> | |||
**[[3mo8]], [[2x4w]], [[2x4x]], [[2x4y]], [[2x35]] – hBRPF1 PWWP domain + histone peptide<br /> | |||
**[[5fg5]], [[5fg4]], [[5myg]] – hBRPF1 bromodomain + chemical probe<br /> | |||
**[[5t4u]], [[5t4v]], [[5mwg]], [[5mwh]], [[5mwz]], [[5o4s]], [[5o4t]], [[5o55]], [[5o5a]], [[5o5f]], [[5o5h]], [[5ov8]], [[5owa]], [[5owb]], [[5owe]], [[6ekq]] – hBRPF1 bromodomain + inhibitor<br /> | |||
**[[5c6s]] – hBRPF1 PWWP domain + ligand <br /> | |||
}} | |||
== '''Available Structures''' == | == '''Available Structures''' == | ||