2x1h: Difference between revisions

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 <StructureSection load='2x1h' size='340' side='right'caption='[[2x1h]], [[Resolution|resolution]] 1.75&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[2x1h]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2X1H OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2X1H FirstGlance]. <br>
+<table><tr><td colspan='2'>[[2x1h]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2X1H OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2X1H FirstGlance]. <br>
-</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene>, <scene name='pdbligand=X1H:[6-HYDROXY-2-(4-HYDROXYPHENYL)-1-BENZOTHIOPHEN-3-YL](4-METHOXYPHENYL)METHANONE'>X1H</scene></td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.75&#8491;</td></tr>
-<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2x7h|2x7h]], [[2wek|2wek]], [[2c0c|2c0c]]</div></td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene>, <scene name='pdbligand=X1H:[6-HYDROXY-2-(4-HYDROXYPHENYL)-1-BENZOTHIOPHEN-3-YL](4-METHOXYPHENYL)METHANONE'>X1H</scene></td></tr>
 <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2x1h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2x1h OCA], [https://pdbe.org/2x1h PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2x1h RCSB], [https://www.ebi.ac.uk/pdbsum/2x1h PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2x1h ProSAT]</span></td></tr>
 </table>
+== Function ==
+[https://www.uniprot.org/uniprot/PTGR3_HUMAN PTGR3_HUMAN] Functions as 15-oxo-prostaglandin 13-reductase and acts on 15-keto-PGE1, 15-keto-PGE2, 15-keto-PGE1-alpha and 15-keto-PGE2-alpha with highest efficiency towards 15-keto-PGE2-alpha. Overexpression represses transcriptional activity of PPARG and inhibits adipocyte differentiation.[UniProtKB:Q8BGC4]
 __TOC__
 </StructureSection>
-[[Category: Human]]
+[[Category: Homo sapiens]]
 [[Category: Large Structures]]
-[[Category: Arrowsmith, C]]
+[[Category: Arrowsmith C]]
-[[Category: Bountra, C]]
+[[Category: Bountra C]]
-[[Category: Chaikuad, A]]
+[[Category: Chaikuad A]]
-[[Category: Edwards, A]]
+[[Category: Edwards A]]
-[[Category: Krojer, T]]
+[[Category: Krojer T]]
-[[Category: Niesen, F]]
+[[Category: Niesen F]]
-[[Category: Oppermann, U]]
+[[Category: Oppermann U]]
-[[Category: Pike, A C.W]]
+[[Category: Pike ACW]]
-[[Category: Shafqat, N]]
+[[Category: Shafqat N]]
-[[Category: Smee, C]]
+[[Category: Smee C]]
-[[Category: Ugochukwu, E]]
+[[Category: Ugochukwu E]]
-[[Category: Weigelt, J]]
+[[Category: Weigelt J]]
-[[Category: Yue, W W]]
+[[Category: Yue WW]]
-[[Category: Oxidoreductase]]
-[[Category: Peroxisome]]