2wp5: Difference between revisions

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<StructureSection load='2wp5' size='340' side='right'caption='[[2wp5]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
<StructureSection load='2wp5' size='340' side='right'caption='[[2wp5]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2wp5]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Tryb2 Tryb2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WP5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2WP5 FirstGlance]. <br>
<table><tr><td colspan='2'>[[2wp5]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Trypanosoma_brucei_brucei_TREU927 Trypanosoma brucei brucei TREU927]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WP5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2WP5 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>, <scene name='pdbligand=MRD:(4R)-2-METHYLPENTANE-2,4-DIOL'>MRD</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=WP5:METHYL+[(4S)-6-BROMO-2-METHYL-4-PHENYLQUINAZOLIN-3(4H)-YL]ACETATE'>WP5</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2wov|2wov]], [[2woi|2woi]], [[2wow|2wow]], [[2wp6|2wp6]], [[2wpe|2wpe]], [[2wpf|2wpf]], [[2wpc|2wpc]]</div></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>, <scene name='pdbligand=MRD:(4R)-2-METHYLPENTANE-2,4-DIOL'>MRD</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=WP5:METHYL+[(4S)-6-BROMO-2-METHYL-4-PHENYLQUINAZOLIN-3(4H)-YL]ACETATE'>WP5</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Trypanothione-disulfide_reductase Trypanothione-disulfide reductase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.8.1.12 1.8.1.12] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2wp5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wp5 OCA], [https://pdbe.org/2wp5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2wp5 RCSB], [https://www.ebi.ac.uk/pdbsum/2wp5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2wp5 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2wp5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wp5 OCA], [https://pdbe.org/2wp5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2wp5 RCSB], [https://www.ebi.ac.uk/pdbsum/2wp5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2wp5 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q389T8_TRYB2 Q389T8_TRYB2]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Tryb2]]
[[Category: Trypanosoma brucei brucei TREU927]]
[[Category: Trypanothione-disulfide reductase]]
[[Category: Alphey MS]]
[[Category: Alphey, M S]]
[[Category: Fairlamb AH]]
[[Category: Fairlamb, A H]]
[[Category: Patterson S]]
[[Category: Patterson, S]]
[[Category: Flavoprotein]]
[[Category: Oxidoreductase]]
[[Category: Redox-active center]]
[[Category: Sleeping sickness]]
[[Category: Trypanosomiasis]]

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